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產(chǎn)品名稱: |
徠卡抗體Anaplastic Lymphoma Kinase |
產(chǎn)品型號: |
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產(chǎn)品產(chǎn)地: |
中國大陸 |
訪問次數(shù): |
1665 |
發(fā)布時間: |
2016/3/28 15:13:38 |
Anaplastic large cell lymphoma (ALCL) is usually composed of large pleomorphic cells which are reported to express CD30 antigen and the epithelial membrane antigen (EMA). |
徠卡抗體Anaplastic Lymphoma Kinase Clone 5A4 7 mL BOND ready-to-use PA0306 P (HIER) Antigen Background Anaplastic large cell lymphoma (ALCL) is usually composed of large pleomorphic cells which are reported to express CD30 antigen and the epithelial membrane antigen (EMA). These tumor cells tend to occur in younger individuals and may be associated with cutaneous and extranodal involvement. A proportion of these cases contain a chromosomal translocation t(2;5) (p23; q35). This results in a hybrid gene encoding part of the nucleophosmin (NPM) gene joined to the cytoplasmic domain of the anaplastic lymphoma kinase (ALK) gene, giving rise to the protein, p80. Large cell lymphomas account for approximately 25 percent of all non-Hodgkin's lymphomas in children and young adults, of which one third carries the NPMALK gene translocation.
Human anaplastic lymphoma: immunohistochemical staining for anaplastic lymphoma kinase (p80) using NCL-ALK. Note cytoplasmic staining of large pleomorphic cells. Paraffin section.
更新時間:2024/11/12 13:40:42
經(jīng)營許可證號:滬寶食藥監(jiān)械經(jīng)營許20220040號
標簽:ALCL 克隆抗體 Anaplastic Lymphoma Kinase
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