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產(chǎn)品展示
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產(chǎn)品名稱: |
徠卡Bcl-2 Oncoprotein蛋白抗體 |
產(chǎn)品型號: |
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產(chǎn)品產(chǎn)地: |
中國大陸 |
訪問次數(shù): |
1534 |
發(fā)布時間: |
2016/3/28 15:40:16 |
Bcl-2 is an integral inner mitochondrial membrane protein of 25 kD and has a wide tissue distribution. It is considered to act as an inhibitor of apoptosis. |
徠卡Bcl-2 Oncoprotein蛋白抗體 Clone bcl-2/100/D5 7 mL BOND ready-to-use PA0117 P (HIER) Antigen Background Bcl-2 is a member of a family of proteins that are involved in apoptosis. Bcl-2 is an integral inner mitochondrial membrane protein of 25 kD and has a wide tissue distribution. It is considered to act as an inhibitor of apoptosis. For this reason, bcl-2 expression is inhibited in germinal centers where apoptosis forms part of the B cell production pathway. In 90 percent of follicular lymphomas a translocation occurs which juxtaposes the bcl-2 gene at 18q21, to an immunoglobulin gene. This t(14;18) translocation can deregulate gene expression and bcl-2 over-expression can be demonstrated immunohistochemically in the vast majority of follicular lymphomas. Also available as a liquid concentrate, refer to page 98
Human diffuse large B cell lymphoma: immunohistochemical staining for Bcl-6 using PA0204. Note nuclear staining of neoplastic cells. Paraffin section.
更新時間:2024/11/12 13:40:42
經(jīng)營許可證號:滬寶食藥監(jiān)械經(jīng)營許20220040號
標簽:蛋白抗體 Bcl-2蛋白 Leica克隆抗體
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