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    產(chǎn)品名稱:

    Beta-Catenin

    產(chǎn)品型號:
    產(chǎn)品產(chǎn)地: 中國大陸
    訪問次數(shù): 1916
    發(fā)布時間: 2016/3/28 16:25:01
    Beta-catenin is a component of the adherens junction, a multiprotein complex which supports Ca2+ -dependent cell to cell contact which in itself is critical for adhesion
  Beta-Catenin
Clone 17C2
7 mL BOND ready-to-use PA0083 P (HIER)
Antigen Background
The catenins, (alpha, beta and gamma) are cytoplasmic proteins which bind
to the highly conserved tail of the E-cadherin molecule. Beta-catenin is a
component of the adherens junction, a multiprotein complex which supports
Ca2+ -dependent cell to cell contact which in itself is critical for adhesion,
signal transmission and for anchoring the actin cytoskeleton. Beta-catenin’s
role is as a transcription effector of the wnt-signalling pathway. Immunohistochemistry is the best way to demonstrate nuclear expression of betacatenin and wnt-pathway activation. This aberrant expression is observed in
human tumorigenesis and especially in colorectal cancer.
Also available as a liquid concentrate, refer to page 100


Colon polyp: immunohistochemical staining with BOND ready-to-use Beta-Catenin (17C2)
using BOND Polymer Refine Detection.

更新時間:2024/11/12 13:40:42


經(jīng)營許可證號:滬寶食藥監(jiān)械經(jīng)營許20220040號


標(biāo)簽:Clone   17C2   抗體   二抗體   

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